We build open-source tools for the inhaled drug delivery and formulation science community. All software is freely available on GitHub.

Dispersibility Analysis Toolkit

Quantifying aerosol dispersibility using the Wasserstein distance

Standard aerosol characterization collapses rich particle size distribution data into summary statistics that obscure clinically relevant variability. This toolkit implements a distribution-sensitive analytical framework based on the Wasserstein distance (Earth Mover's Distance) to quantify how closely an inhaler-generated aerosol approaches a powder's intrinsic dispersion limit. The metric is formulation-agnostic, physically interpretable, and works with standard laser diffraction data.

Language: R

Publication: Xia G, Dechayont B, Che L, Comfort I, Brunaugh AD. A distribution-based metric for quantifying dispersibility in dry powder inhalers. Pharmaceutics, 2026.

Data: Raw laser diffraction datasets (Deep Blue Data)

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